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Health insights, product news, and supplement science from the Alise Pharma team.

New Product

Sleep & Restore Formula Now Available

RK
Dr. Robert Kim
VP of Product Development
November 20, 20256 min read

We are excited to announce that Sleep & Restore, our newest supplement formulation, is now available for purchase. After 18 months of development and testing, we have created a sleep support formula that addresses the most common complaints we hear from customers: difficulty falling asleep, restless nights, and waking up feeling unrested. Sleep & Restore combines three clinically studied ingredients — magnesium glycinate, L-theanine, and low-dose melatonin — in a precise formulation designed to support every phase of your sleep cycle.

Sleep is foundational to health. It affects everything from immune function and hormone regulation to cognitive performance and emotional resilience. Yet an estimated one in three adults consistently fails to get the recommended seven to nine hours of quality sleep. We built Sleep & Restore for those people — not as a sedative or a shortcut, but as a science-backed tool to help the body do what it is naturally designed to do.

The Science Behind Magnesium Glycinate

Magnesium is involved in over 300 enzymatic reactions in the body, and its role in sleep regulation is well documented. It activates the parasympathetic nervous system — the branch responsible for calming and relaxing the body — and helps regulate melatonin production. Studies have shown that magnesium supplementation can improve subjective sleep quality, sleep time, and sleep efficiency, particularly in individuals with low magnesium status.

We chose the glycinate form specifically because of its superior bioavailability and gentle gastrointestinal profile. Unlike magnesium oxide or citrate, which can cause digestive discomfort at higher doses, magnesium glycinate is chelated with the amino acid glycine. Glycine itself has calming properties — it has been shown to lower core body temperature at bedtime, a key physiological trigger for sleep onset. So with magnesium glycinate, you get a dual-action benefit: the magnesium supports nervous system relaxation while the glycine aids the body's natural temperature regulation for sleep.

Sleep & Restore contains 400 mg of magnesium glycinate per serving, providing 200 mg of elemental magnesium — a dose consistent with the amounts used in clinical studies showing meaningful improvements in sleep quality.

L-Theanine for Calm Without Drowsiness

L-theanine is an amino acid found naturally in green tea. It promotes relaxation without sedation by increasing alpha brain wave activity — the same brain wave pattern associated with a calm, meditative state. Unlike pharmaceutical sleep aids that forcibly depress the central nervous system, L-theanine simply helps the mind settle into a state of quiet alertness that makes the transition to sleep more natural.

Research has shown that 200 mg of L-theanine taken before bedtime can reduce resting heart rate, improve sleep quality scores, and decrease sleep latency (the time it takes to fall asleep). Importantly, L-theanine does not cause morning grogginess — a critical differentiator from many prescription and over-the-counter sleep medications. Participants in clinical studies report waking feeling refreshed rather than sluggish.

Our formula includes 200 mg of pharmaceutical-grade L-theanine per serving, sourced from a supplier whose product has been used in multiple published clinical trials.

Low-Dose Melatonin: Less Is More

Melatonin is the most widely used sleep supplement in the world, but it is frequently misused. Many commercial products contain 5 to 10 mg of melatonin per serving — far more than the body naturally produces and well above the doses shown to be most effective in clinical research. High-dose melatonin can actually disrupt the sleep cycle, causing vivid dreams, next-day drowsiness, and reduced endogenous melatonin production over time.

Sleep & Restore uses just 0.5 mg of melatonin — a physiologic dose that mirrors the body's natural nighttime production. Research from MIT, where melatonin's sleep effects were first characterized, has shown that doses in the 0.3 to 1.0 mg range are sufficient to raise blood melatonin levels to their normal nighttime peak without overloading receptors. This low-dose approach helps signal to the brain that it is time to sleep while preserving the body's natural melatonin rhythm.

We deliberately chose this conservative dose because our philosophy is to work with the body, not override it. Sleep & Restore is designed for nightly use without the risk of tolerance or dependence that can accompany higher melatonin doses.

How to Use Sleep & Restore

Take two capsules approximately 30 to 60 minutes before your target bedtime. We recommend establishing a consistent routine — taking Sleep & Restore at the same time each night helps reinforce your circadian rhythm. For best results, pair with basic sleep hygiene practices: reduce screen exposure in the hour before bed, keep your bedroom cool and dark, and maintain a consistent wake time, even on weekends.

Sleep & Restore is non-habit-forming and safe for daily use. However, as with any supplement, we recommend consulting with your healthcare provider before starting, especially if you are taking prescription medications, are pregnant or nursing, or have a diagnosed sleep disorder. This product is intended to support healthy sleep patterns, not to treat clinical insomnia or other medical conditions.

What Makes Sleep & Restore Different

The sleep supplement market is crowded, and many products rely on proprietary blends that obscure actual ingredient amounts, or load up on sedating herbs at doses with limited clinical support. Sleep & Restore takes the opposite approach: every ingredient is listed at its exact dose on the label, every dose is consistent with published clinical research, and the formulation contains no proprietary blends, artificial colors, or unnecessary fillers.

Like all Alise Pharma products, Sleep & Restore undergoes third-party testing for purity, potency, and contaminants. Each batch comes with a Certificate of Analysis accessible through the QR code on the packaging. We believe that if you are putting something in your body every night, you deserve to know exactly what is in it — and that it has been independently verified.

Key Takeaways

  • Sleep & Restore combines magnesium glycinate (200 mg elemental), L-theanine (200 mg), and low-dose melatonin (0.5 mg) in a clinically informed formula.
  • Magnesium glycinate supports nervous system relaxation and natural temperature regulation for sleep onset.
  • L-theanine promotes calm alpha brain wave activity without causing morning grogginess.
  • The 0.5 mg melatonin dose is a physiologic amount that works with the body's natural rhythm, avoiding the side effects of high-dose melatonin products.
  • Fully transparent labeling with no proprietary blends, plus third-party tested with batch-level Certificates of Analysis.
RK
Dr. Robert Kim
VP of Product Development at Alise Pharma

Dr. Robert Kim leads product development at Alise Pharma, overseeing formulation, stability testing, and manufacturing partnerships. With a Pharm.D. from the University of Michigan and a decade of experience in pharmaceutical product development, Robert is dedicated to creating supplements that meet the same quality standards as prescription medications. He specializes in bioavailability optimization and evidence-based formulation design.